δ-Protocadherins: Organizers of neural circuit assembly
نویسندگان
چکیده
منابع مشابه
Chemoaffinity Revisited: Dscams, Protocadherins, and Neural Circuit Assembly
The chemoaffinity hypothesis for neural circuit assembly posits that axons and their targets bear matching molecular labels that endow neurons with unique identities and specify synapses between appropriate partners. Here, we focus on two intriguing candidates for fulfilling this role, Drosophila Dscams and vertebrate clustered protocadherins (Pcdhs). In each, a complex genomic locus encodes la...
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ژورنال
عنوان ژورنال: Seminars in Cell & Developmental Biology
سال: 2017
ISSN: 1084-9521
DOI: 10.1016/j.semcdb.2017.07.037